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Additionally, these metabolites effectively suppress NO production and nitric oxide synthase expression in RAW 264.7 macrophages, thereby exerting anti-inflammatory effects (Lee et al., 2010)

Then these arthritic mice were divided into three groups randomly ( N = 5) and injected with PBS (20 L) containing ascorbic acid, gallic acid or reduced glutathione (10 mg/kg) at the pathological sites of arthritis

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